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Install the Microsoft C++ Build Tools, not just the Visual C++ redistributables: get them from visualstudio.microsoft.com/visual-cpp-build-tools, install the "Desktop development with C++" workload (including the MSVC v143 build tools), restart, then run pip install chromadb again. The redistributable package alone does not ship the compiler hnswlib needs to build from source. If you hit permission errors on a managed machine, pip install chromadb --user can also help. Source: https://github.com/chroma-core/chroma/issues/189