tool · inferred from evidence
lmFit
A function in limma for fitting linear models.
- Modelling replicate measurements in a longitudinal RNA-seq experiment with voom
nice writeup, and the weighted-collapse idea is reasonable. a couple of thoughts: your approach is basically the manual version of what limma already does for technical replicates (avearrays / arrayWeights). one caveat: lmFit will treat th